Some of Melissa’s first settlers came from the old Highlands community, two and a half miles north of present-day Melissa. C.H. Wysong was one of the earliest settlers. A post office was established in 1853. The Houston and Texas Central Railroad was built in Melissa in 1872. The town was laid out at this time. The railroad encouraged many families to come to Melissa. The town is believed to have been named for the daughter of a railroad executive, George A. Quinlan (1838–1901) of the Houston and Texas Central Railroad. There is some disagreement about this, as others argue that the town was named after Melissa Huntington, daughter of C. P. Huntington, another well-known railroad executive. Anna, Texas, is named after Anna Elizabeth Quinlan (1878–1952), the only daughter of George Austin Quinlan and his wife Mary Kate Saunders (1851–1884). Quinlan, Texas, is named after George Austin Quinlan himself.
Melissa was an important shipping point in the early 1900s. Corn, wheat, alfalfa hay, wood, and livestock were all sent out on the railroad.
Population of Melissa, TX
Last official estimated population of Melissa city (Collin County**, Texas state) was 6,703 (year 2014). This was 0.002% of total US population and 0.02% of total Texas state population. Area of Melissa city is 10.2 mi² (=26.4 km²), in this year population density was 658.58 p/mi². If population growth rate would be same as in period 2010-2014 (+9.31%/yr), Melissa city population in 2017 would be 8,755*.
*Calculated by population.us from last known population growth rate, not official data.